
Availability: In Stock
The Hornady InterLock 45 caliber 350 grain round nose bullet is a serious choice for handloaders working up ammunition for large-frame rifles and powerful cartridges. Built around Hornady's time-tested InterLock ring system, this bullet locks the lead core to the copper jacket during expansion, which translates to reliable energy transfer and consistent terminal performance on big game. The round nose profile and 350 grain weight make these bullets well-suited for magnum rifle cartridges where velocity and impact dynamics demand a tough, controlled-expansion design.
InterLock bullets have earned their place in handloaders' boxes because they deliver predictable expansion without fragmenting, a critical trait when hunting large or dangerous game where shot placement matters and a second opportunity may not present itself. The one-piece core and jacket construction contributes to the weight retention that seasoned hunters rely on—the bullet stays together through the animal, maximizing the wound channel rather than shedding energy in fragmentation. This is especially important when your shot has to count in the field.
Whether you're loading for an antique rifle, a favorite magnum, or experimenting with a new wildcat, Hornady's quality control and consistent performance across a box of 50 means your handloaded ammunition will shoot more predictably than pulling random components together. The 350 grain weight in round nose configuration is not common—verify your rifle's twist rate and magazine length before committing to a load, as heavier, longer bullets demand respect during development.
| Caliber | 45 |
| Weight | 350 grains |
| Nose Profile | Round Nose |
| Quantity per Box | 50 |
These are 45 caliber bullets intended for large-frame rifle cartridges. You'll need to verify that your rifle's bore diameter is .458 inches and that your magazine or loading setup can physically accommodate a 350 grain, round nose bullet. Consult your rifle's manual and your chosen cartridge's reloading data before ordering.
Hornady's InterLock ring is a mechanical locking groove that binds the lead core to the copper jacket. During expansion, this keeps the core and jacket moving together rather than separating, which preserves weight and creates a larger, more effective wound channel—critical for ethical, one-shot kills on big game.
These are intermediate to advanced handloading components. The 350 grain weight and round nose profile require proper reloading data, a scale accurate to the grain, and careful load development. If you're new to handloading, start with factory ammunition or consult an experienced reloader to ensure safe, consistent results.
One box contains 50 Hornady InterLock 45 caliber, 350 grain round nose bullets—no powder, primers, or brass included.
SKU: 115699565 • Width: 3in • Height: 1in • Depth: 4in • Weight: 2oz





Availability: In Stock
The Hornady InterLock 45 caliber 350 grain round nose bullet is a serious choice for handloaders working up ammunition for large-frame rifles and powerful cartridges. Built around Hornady's time-tested InterLock ring system, this bullet locks the lead core to the copper jacket during expansion, which translates to reliable energy transfer and consistent terminal performance on big game. The round nose profile and 350 grain weight make these bullets well-suited for magnum rifle cartridges where velocity and impact dynamics demand a tough, controlled-expansion design.
InterLock bullets have earned their place in handloaders' boxes because they deliver predictable expansion without fragmenting, a critical trait when hunting large or dangerous game where shot placement matters and a second opportunity may not present itself. The one-piece core and jacket construction contributes to the weight retention that seasoned hunters rely on—the bullet stays together through the animal, maximizing the wound channel rather than shedding energy in fragmentation. This is especially important when your shot has to count in the field.
Whether you're loading for an antique rifle, a favorite magnum, or experimenting with a new wildcat, Hornady's quality control and consistent performance across a box of 50 means your handloaded ammunition will shoot more predictably than pulling random components together. The 350 grain weight in round nose configuration is not common—verify your rifle's twist rate and magazine length before committing to a load, as heavier, longer bullets demand respect during development.
| Caliber | 45 |
| Weight | 350 grains |
| Nose Profile | Round Nose |
| Quantity per Box | 50 |
These are 45 caliber bullets intended for large-frame rifle cartridges. You'll need to verify that your rifle's bore diameter is .458 inches and that your magazine or loading setup can physically accommodate a 350 grain, round nose bullet. Consult your rifle's manual and your chosen cartridge's reloading data before ordering.
Hornady's InterLock ring is a mechanical locking groove that binds the lead core to the copper jacket. During expansion, this keeps the core and jacket moving together rather than separating, which preserves weight and creates a larger, more effective wound channel—critical for ethical, one-shot kills on big game.
These are intermediate to advanced handloading components. The 350 grain weight and round nose profile require proper reloading data, a scale accurate to the grain, and careful load development. If you're new to handloading, start with factory ammunition or consult an experienced reloader to ensure safe, consistent results.
One box contains 50 Hornady InterLock 45 caliber, 350 grain round nose bullets—no powder, primers, or brass included.
SKU: 115699565 • Width: 3in • Height: 1in • Depth: 4in • Weight: 2oz