
Availability: In Stock
The Hornady Custom Grade Series I 2-Die Set for 22-250 Rem gives you the core tools you need to reload this popular varmint and medium-game cartridge with precision and confidence. This two-die rifle reloading set includes a full-length sizing die and a bullet seater die, both built with Hornady's reputation for reliable, long-lasting performance. Whether you're working up loads at the bench or running production ammo for the range, this set handles the essential sizing and seating steps in a straightforward, dependable package.
What sets Hornady's Series I dies apart is attention to the details that actually matter during your reloading sessions. The sizing die features the Zip Spindle Design with fine and coarse thread options—you can make precise incremental adjustments by turning the spindle, or zip it up or down quickly for larger changes. The internal profile is precision-machined and polished smooth to prevent case sticking and excessive friction, so you're not fighting your press on every stroke. The elliptical expander technology provides smooth, even neck sizing with significantly reduced friction compared to traditional ball expanders, and it eliminates case neck stretch in ways that show up in better, more consistent loads.
The seating die brings benchrest-level alignment to your ammunition. Hornady's in-line bullet seating system holds the bullet, case neck, and seating stem in perfect alignment before the bullet even enters the case neck. That means bullets are centered and seated consistently, shot after shot—the kind of precision that matters when you're chasing tight groups or dialing in a load. A built-in crimper is included, so you can finish your rounds without dedicating a separate press station or buying an extra die. The Sure-Loc lock rings clamp with constant pressure and tighten without contacting the threads, so they stay put without pliers or wrench damage.
Everything arrives in a compartmentalized box designed to keep your dies, bushings, and shell holders organized and easy to find. Hornady backs this set with a no-risk lifetime warranty—they stand behind the craftsmanship because these dies are engineered to last through normal use without breaking or wearing out.
| Product Name | Hornady Custom Grade Series I 2-Die Set for 22-250 Rem |
| Part Number | 546220 |
| Cartridge | 22-250 Rem |
| Die Count | 2 (sizing die, seater die) |
| Brand | Hornady |
| Series | Custom Grade Series I |
The set includes a full-length sizing die with Zip Spindle Design and a bullet seater die with built-in crimper. These are the two essential dies for the primary sizing and seating steps of rifle reloading.
Yes. The seater die features a built-in crimper, so you can crimp your finished rounds without purchasing a separate crimp die or using an additional press station.
Hornady's elliptical expander provides significantly smoother neck sizing with reduced friction and case neck stretch compared to traditional ball expanders. Internal threading also prevents it from pulling loose during operation.
Yes. Hornady backs this set with a no-risk lifetime warranty that guarantees the dies will not break or wear out from normal use.


SKU: 115716464 • Width: 4.9in • Height: 1.9in • Depth: 7.3in • Weight: 1.38oz
Availability: In Stock
The Hornady Custom Grade Series I 2-Die Set for 22-250 Rem gives you the core tools you need to reload this popular varmint and medium-game cartridge with precision and confidence. This two-die rifle reloading set includes a full-length sizing die and a bullet seater die, both built with Hornady's reputation for reliable, long-lasting performance. Whether you're working up loads at the bench or running production ammo for the range, this set handles the essential sizing and seating steps in a straightforward, dependable package.
What sets Hornady's Series I dies apart is attention to the details that actually matter during your reloading sessions. The sizing die features the Zip Spindle Design with fine and coarse thread options—you can make precise incremental adjustments by turning the spindle, or zip it up or down quickly for larger changes. The internal profile is precision-machined and polished smooth to prevent case sticking and excessive friction, so you're not fighting your press on every stroke. The elliptical expander technology provides smooth, even neck sizing with significantly reduced friction compared to traditional ball expanders, and it eliminates case neck stretch in ways that show up in better, more consistent loads.
The seating die brings benchrest-level alignment to your ammunition. Hornady's in-line bullet seating system holds the bullet, case neck, and seating stem in perfect alignment before the bullet even enters the case neck. That means bullets are centered and seated consistently, shot after shot—the kind of precision that matters when you're chasing tight groups or dialing in a load. A built-in crimper is included, so you can finish your rounds without dedicating a separate press station or buying an extra die. The Sure-Loc lock rings clamp with constant pressure and tighten without contacting the threads, so they stay put without pliers or wrench damage.
Everything arrives in a compartmentalized box designed to keep your dies, bushings, and shell holders organized and easy to find. Hornady backs this set with a no-risk lifetime warranty—they stand behind the craftsmanship because these dies are engineered to last through normal use without breaking or wearing out.
| Product Name | Hornady Custom Grade Series I 2-Die Set for 22-250 Rem |
| Part Number | 546220 |
| Cartridge | 22-250 Rem |
| Die Count | 2 (sizing die, seater die) |
| Brand | Hornady |
| Series | Custom Grade Series I |
The set includes a full-length sizing die with Zip Spindle Design and a bullet seater die with built-in crimper. These are the two essential dies for the primary sizing and seating steps of rifle reloading.
Yes. The seater die features a built-in crimper, so you can crimp your finished rounds without purchasing a separate crimp die or using an additional press station.
Hornady's elliptical expander provides significantly smoother neck sizing with reduced friction and case neck stretch compared to traditional ball expanders. Internal threading also prevents it from pulling loose during operation.
Yes. Hornady backs this set with a no-risk lifetime warranty that guarantees the dies will not break or wear out from normal use.
SKU: 115716464 • Width: 4.9in • Height: 1.9in • Depth: 7.3in • Weight: 1.38oz

